Download Files:
Homo-PROTAC pVHL30 degrader 1
$160 – $1,020
Products Details
Product Description
– Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC[1], consists of two ligands of von Hippel-Lindau.
Web ID
– HY-111593
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C58H82N8O14S2
References
– [1]Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.
CAS Number
– 2244684-49-7
Molecular Weight
– 1179.45
Compound Purity
– 99.83
SMILES
– CC1=C(C2=CC=C(CNC([C@@H]3C[C@@]([H])(O)CN3C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)C[C@@]([H])(O)C4)=O)=O)=O)=O)=O)C=C2)SC=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 150 mg/mL|H2O : 25 mg/mL (ultrasonic)
Target
– PROTACs
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
