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Products Details
Product Description
– Homo-BacPROTAC6 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis[1].
Web ID
– HY-153571
Shipping
– Room temperature
Molecular Formula
– C112H164N22O22
References
– [1]Hoi DM, et al. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell. 2023 May 11;186(10):2176-2192.e22.
Molecular Weight
– 2170.63
SMILES
– O=C(N[C@H](C(N(C)[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC1=CN(CC2=CN(CCOCCOCCOCCOCCN3C=C(CN4C=C(C[C@@H]5NC([C@@H](NC([C@@H](N(C)C([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H](C[C@@H](C)CO)N(C)C5=O)=O)C)=O)[C@@H](C6=CC=CC=C6)OC)=O)=O)CC(C)C)=O)C(C)C)=O)C7=C4C=CC=C7)N=N3)N=N2)C8=C1C=CC=C8)C9=O)=O)=O)CC(C)C)=O)C(C)C)[C@@H](NC([C@H](C)NC([C@H](C[C@H](CO)C)N9C)=O)=O)[C@H](OC)C%10=CC=CC=C%10
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;PROTACs
Pathway
– Anti-infection;PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
