Halazone

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Products Details

Product Description

– Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].

Web ID

– HY-B1386

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C7H5Cl2NO4S

References

– [1]M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64.|[2]Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.

CAS Number

– 80-13-7

Molecular Weight

– 270.09

Compound Purity

– 75.0

SMILES

– O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1

Clinical Information

– Launched

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Bacterial;Carbonic Anhydrase;Sodium Channel

Isoform

– CA Ⅱ

Pathway

– Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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