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Halazone
SKU
HY-B1386-100 mg
Category Reference compound
Tags Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease, Bacterial;Carbonic Anhydrase;Sodium Channel, Infection
$45 – $100
Products Details
Product Description
– Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].
Web ID
– HY-B1386
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C7H5Cl2NO4S
References
– [1]M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64.|[2]Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.
CAS Number
– 80-13-7
Molecular Weight
– 270.09
Compound Purity
– 75.0
SMILES
– O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Bacterial;Carbonic Anhydrase;Sodium Channel
Isoform
– CA Ⅱ
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
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