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HA130
$66 – $330
Products Details
Product Description
– HA130 is a selective autotaxin (ATX) inhibitor with an IC50 of 28 nM.
Web ID
– HY-19329
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H19BFNO5S
References
– [1]Zhang Y, et al. Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. J Immunol. 2012 Oct 15;189(8):3914-3924.|[2]Bai Z, et al. Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by theautotaxin/lysophosphatidic acid axis. J Immunol. 2013 Mar 1;190(5):2036-2048.
CAS Number
– 1229652-21-4
Molecular Weight
– 463.29
Compound Purity
– 99.46
SMILES
– O=C1N(CC2=CC=C(F)C=C2)C(S/C1=CC3=CC=C(OCC4=CC(B(O)O)=CC=C4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 39 mg/mL
Target
– Phosphodiesterase (PDE)
Isoform
– Autotaxin
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
