GW274150
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GW274150

SKU T11518L-1 mg Category Brand:

Price range: 51 CAD through 1,059 CAD

Products Details

Product Description

– GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.

Web ID

– T11518L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C8H17N3O2S

References

– Alderton WK, et al. GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo.Br J Pharmacol. 2005 Jun;145(3):301-12.

CAS Number

– 210354-22-6

Molecular Weight

– C8H17N3O2S

Compound Purity

– 0.9643

SMILES

– C([C@@H](C(O)=O)N)CSCCNC(C)=N

Target

– COX|||DNA/RNA Synthesis

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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