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GW 590735
SKU
HY-106278-10 mg
Category Reference compound
Tags Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor, Metabolic Disease, PPAR
$260 – $2,030
Products Details
Product Description
– GW 590735 is a potent and selective PPARα agonist. GW 590735 showsEC50=4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW 590735 can be used for the research of dyslipidemia[1].
Web ID
– HY-106278
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H21F3N2O4S
References
– [1]Sierra ML, et al. Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents. J Med Chem. 2007;50(4):685-695.
CAS Number
– 343321-96-0
Molecular Weight
– 478.48
Compound Purity
– 98.87
SMILES
– OC(C(C)(C)OC(C=C1)=CC=C1CNC(C2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=O)=O
Clinical Information
– Phase 2
Research Area
– Metabolic Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– PPAR
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.