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GsMTx4 TFA (1209500-46-8 free base)
Price range: 468 USD through 2,150 USD
Products Details
Product Description
– GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
Web ID
– TP1300
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C187H279N48O48S6F3
Citations
– 1. Chen L, Yan Y, Kong F, et al. Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells. Cancers. 2022, 14(8): 2036
2. Piezo1 regulates colon stem cells to maintain epithelial homeostasis through SCD1-Wnt-β-catenin and programming fatty acid metabolism
References
– Gnanasambandam R, et al. GsMTx4: Mechanism of Inhibiting Mechanosensitive Ion Channels. Biophys J. 2017 Jan 10;112(1):31-45.
Molecular Weight
– C187H279N48O48S6F3
Compound Purity
– 0.9981
SMILES
– [H]NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N1CCC[C@H]1C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)CS)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)CS)=O)=O)=O)=O)=O)=O)CS)=O)CS)=O)=O)CC(O)=O)=O)CC(O)=O)=O)=O)=O)=O)CS)=O)=O)CC6=CNC7=C6C=CC=C7)=O)CC8=CNC9=C8C=CC=C9)=O)CC%10=CC=CC=C%10)=O)=O)=O)CS)=O.O=C(O)C(F)(F)F
Pathway
– Membrane transporter/Ion channel
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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