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GSK 189254 HCl
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– GSK 189254A is a histamine H3 receptor antagonist for the treatment of narcolepsy. Histamine H3 receptor antagonists have been shown to increase the release of neurotransmitters in the brain and to enhance cognition in vivo. The compound may also be useful in the treatment of dementia and neuropathic pain.
Web ID
– T19628
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H26ClN3O2
References
– Schou M, Varnäs K, Jureus A, Ahlgren C, Malmquist J, Häggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnström P, Finnema SJ, Nakao R, Amini N, Takano A, Farde L. Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor. ACS Chem Neurosci. 2016 Feb 17;7(2):177-84. doi: 10.1021/acschemneuro.5b00268. Epub 2015 Nov 30. PubMed PMID: 26529287.
CAS Number
– 945493-87-8
Molecular Weight
– C21H26ClN3O2
SMILES
– Cl.O=C(NC)C1=CN=C(OC2=CC=C3C(=C2)CCN(CC3)C4CCC4)C=C1
Target
– CDK|||Apoptosis|||GSK-3
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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