GSK-1070916

SKU T6129-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 1,037 CAD

Products Details

Product Description

– GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.

Web ID

– T6129

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H33N7O

References

– Anderson K, et al. Biochem J, 2009, 420(2), 259-265.

CAS Number

– 942918-07-2

Molecular Weight

– C30H33N7O

Compound Purity

– 0.9851

SMILES

– CCn1cc(c(n1)-c1ccc(NC(=O)N(C)C)cc1)-c1ccnc2[nH]c(cc12)-c1cccc(CN(C)C)c1

Pathway

– Angiogenesis|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||Apoptosis|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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