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GS143
Price range: 51 CAD through 923 CAD
Products Details
Product Description
– GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. It suppresses NF-κB activation and transcription of target genes without inhibiting proteasome activity. GS143 has anti-asthm[atic] properties.
Web ID
– T25465
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H19FN2O4
References
– Rashmi BS, Gayathri D. Molecular characterization of gluten hydrolysing Bacillus sp. and their efficacy and biotherapeutic potential as probiotics using Caco-2 cell line. J Appl Microbiol. 2017 Sep;123(3):759-772. doi: 10.1111/jam.13517. Epub 2017 Aug 4. PubMed PMID: 28637081.
CAS Number
– 916232-21-8
Molecular Weight
– C28H19FN2O4
Compound Purity
– 0.9767
SMILES
– OC(=O)c1ccc(cc1)N1N=C(Cc2ccccc2)C(=C/c2ccc(o2)-c2ccccc2F)C1=O
Pathway
– NF-κB|||Ubiquitination
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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