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Products Details
Product Description
– GS-443902 trisodium (GS-441524 triphosphate trisodium), the active triphosphate metabolite of Remdesivir (GS-5734), serves as a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), displaying inhibitory concentrations (IC50) of 1.1 μM for RSV RdRp and 5 μM for HCV RdRp.
Web ID
– T38761
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H16N5O13P3.xNa
References
– Siegel D, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. Med Chem. 2017 Mar 9;60(5):1648-1661.
CAS Number
– 1355050-21-3
SMILES
– C(#N)[C@]1(O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)[C@H]1O)C=2N3C(=CC2)C(N)=NC=N3.[Na]
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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