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Products Details
Product Description
– GS 389 ((±)-O,O-Dimethylcoclaurine) is a tetrahydroisoquinoline. GS-389 inhibites Cyclic AMP and cyclic AMP dependent phosphodiesterases from rat atrial and ventricular tissue. GS-389 relaxes the contraction induced by phenylephrine and high K+ in rat aortic rings[1].
Web ID
– HY-129665
Shipping
– Room temperature
Molecular Formula
– C19H23NO3
References
– [1]Chang KC, et al. Different pharmacological characteristics of structurally similar benzylisoquinoline analogs, papaverine, higenamine, and GS 389, on isolated rat aorta and heart. Can J Physiol Pharmacol. 1994;72(4):327-334.
CAS Number
– 41498-37-7
Molecular Weight
– 313.39
SMILES
– COC1=CC=C(CC2NCCC3=C2C=C(OC)C(OC)=C3)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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