Download Files:
Products Details
Product Description
– GRP78-IN-2 (Compound FL5) is a GRP78 (Glucose Regulated Protein 78 kDa) inhibitor. GRP78-IN-2 preferentially targeting cell surface GRP78 and shows potent antiangiogenic and anticancer activities without affecting other normal cells[1].
Web ID
– HY-146420
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H29NO6
References
– [1]Qiao Y, et al. Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy. Eur J Med Chem. 2020 May 1;193:112228.
CAS Number
– 1882875-63-9
Molecular Weight
– 487.54
SMILES
– COC1=CC(OC)=CC(C(OCC2=CC=C(C=C2)C3=C(C4=CC=CC=C4O3)C(NCC(C)C)=O)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– HSP
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
