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Products Details
Product Description
– Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimer’s disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.
Web ID
– TN1037
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H16NO4
References
– Research on bitter components from Coptis chinensis based on electronic tongue.Zhongguo Zhong Yao Za Zhi. 2014 Sep;39(17):3326-9.
CAS Number
– 38691-95-1
Molecular Weight
– C19H16NO4
Compound Purity
– 0.9977
SMILES
– O(C)C=1C=C2C=3[N+](=CC4=C(C3)C=CC5=C4OCO5)CCC2=CC1O
Pathway
– DNA Damage/DNA Repair
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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