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Grb2 SH2 domain inhibitor 1 (TFA)

SKU HY-146127A-1 mg Category Tag

$110$520

Products Details

Product Description

– Grb2 SH2 domain inhibitor 1 TFA is a conformationally restricted cyclic cell penetrating peptide (CPP) containing d-pro-l-pro motif ring (AF Φ Rpprrfq) (where Φ It is L-naphthylalanine, R is D-arginine, P is D-proline), which is mainly used as a cyclic peptide inhibitor.

Web ID

– HY-146127A

Storage Temperature

– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Shipping

– Blue Ice

Molecular Formula

– C68H95N20O15P.xC2HF3O2

References

– [1]Wen J,et al. Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif. Bioorg Med Chem. 2020 Oct 15;28(20):115711.

Molecular Weight

– 1463.58 (free base)

Compound Purity

– 99.71

SMILES

– CC([C@@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]2CCCN2C([C@H]3CCCN3C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(N)=O)=O)CC4=CC=CC=C4)=O)CC5=CC=C6C=CC=CC6=C5)=O)CCCNC(N)=N)=O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC7=CC=C(C=C7)OP(O)(O)=O)=O)C.OC(C(F)(F)F)=O.[x]

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : ≥ 100 mg/mL

Target

– Others

Pathway

– Others

Product type

– Peptides

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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