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Graveoline
SKU
HY-12538-5 mg
Category Reference compound
Tags Anti-infection;Apoptosis;Autophagy, Apoptosis;Autophagy;Fungal, Cancer; Infection
$50
Only 1000 item(s) left in stock.
Products Details
Product Description
– Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].
Web ID
– HY-12538
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C17H13NO3
References
– [1]Ghosh S, et, al. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014 Aug;28(8):1153-62.|[2]Kamal LZM, et, al. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May;186(2):221-236.
CAS Number
– 485-61-0
Molecular Weight
– 279.29
Compound Purity
– 99.96
SMILES
– O=C1C=C(C2=CC=C(OCO3)C3=C2)N(C)C4=C1C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy;Fungal
Pathway
– Anti-infection;Apoptosis;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.