GR231118

SKU TP2022-5 mg Category Brand:

1,653 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively). Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively). Suppresses food intake in rats in vivo. Also has affinity for neuropeptide FF (NPFF) receptors in vitro (Ki = 43-73 nM).

Web ID

– TP2022

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C110H170N34O24

References

– Ishihara et al (1998) A potent neuropeptide Y antagonist, 1229U91, suppressed spontaneous food intake in Zucker fatty rats. Am.J.Physiol. 274 R1500 PMID:

CAS Number

– 158859-98-4

Molecular Weight

– C110H170N34O24

SMILES

– O=C1N2[C@](C(=O)N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)CNC(=O)CC[C@H](NC([C@H]([C@H](CC)C)N)=O)C(=O)N5C(C(=O)N[C@H](C(N[C@@H](CC6=CC=C(O)C=C6)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CC=C(O)C=C7)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)CNC(=O)CC[C@@H]1NC([C@H]([C@H](CC)C)N)=O)(CCC5)[H])(CCC2)[H]

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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