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GPR35 agonist 2
SKU
HY-15705-10 mg
Category Reference compound
Tags Arrestin;GPR35, GPCR/G Protein, Metabolic Disease; Inflammation/Immunology
$130 – $1,300
Products Details
Product Description
– GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].
Web ID
– HY-15705
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C17H11FN2O3S
References
– [1]Thimm D, et, al. 6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56(17): 7084-99.
CAS Number
– 494191-73-0
Molecular Weight
– 342.34
Compound Purity
– 98.84
SMILES
– O=C(O)C1=CC=C(/C=C(SC(NC2=CC=CC=C2F)=N3)C3=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Arrestin;GPR35
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.