GPR35 agonist 2

$130$1,300

Products Details

Product Description

– GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].

Web ID

– HY-15705

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C17H11FN2O3S

References

– [1]Thimm D, et, al. 6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56(17): 7084-99.

CAS Number

– 494191-73-0

Molecular Weight

– 342.34

Compound Purity

– 98.84

SMILES

– O=C(O)C1=CC=C(/C=C(SC(NC2=CC=CC=C2F)=N3)C3=O)C=C1

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Inflammation/Immunology

Solubility

– DMSO : 25 mg/mL (ultrasonic)

Target

– Arrestin;GPR35

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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