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Glycochenodeoxycholic acid
SKU
HY-N2334-10 mg
Category Natural Products
Tags Apoptosis;Endogenous Metabolite, Apoptosis;Metabolic Enzyme/Protease, Cancer
$38 – $66
Products Details
Product Description
– Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].
Web ID
– HY-N2334
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H43NO5
References
– [1]Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.|[2]Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.
CAS Number
– 640-79-9
Molecular Weight
– 449.62
Compound Purity
– 98.0
SMILES
– C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCC(O)=O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@](C[C@H](O)CC4)([H])C[C@H]3O)C)([H])CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis;Endogenous Metabolite
Isoform
– Human Endogenous Metabolite;Microbial Metabolite
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Natural Products
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