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Glucosamine
$32 – $180
Products Details
Product Description
– Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Web ID
– HY-B1125
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H13NO5
Citations
– Microbiome. 2019 Mar 20;7(1):43. |Theranostics. 2021 Mar 24;11(12):5650-5674.|Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.
References
– [1]Bruyère O, et al. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S12-7.|[2]Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.|[3]Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706.|[4]Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84.
CAS Number
– 3416-24-8
Molecular Weight
– 179.17
Compound Purity
– 98.0
SMILES
– O=C[C@H](N)[C@H]([C@@H]([C@@H](CO)O)O)O
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 3.33 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Autophagy;Endogenous Metabolite;HIF/HIF Prolyl-Hydroxylase;Reactive Oxygen Species
Isoform
– Human Endogenous Metabolite
Pathway
– Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
