Ginsenoside Rk3

$104$620

Products Details

Product Description

– Ginsenoside Rk3 is present in the roots Panax ginseng herbs. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells.

Web ID

– HY-N0906

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C36H60O8

References

– [1]Cho K, et al. Inhibition of TNF-α-Mediated NF-κB Transcriptional Activity by Dammarane-Type Ginsenosidesfrom Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells. Biomol Ther (Seoul). 2014 Jan;22(1):55-61.|[2]Duan Z, et al. Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo. Food Funct. 2017 Oct 18;8(10):3723-3736.

CAS Number

– 364779-15-7

Molecular Weight

– 620.86

Compound Purity

– 98.85

SMILES

– C[C@@]([C@@]12C)(C[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO)[C@@]4([H])C5(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@@H](C(CC/C=C(C)/C)=C)CC2)([H])[C@]4(CC[C@@H]5O)C

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– NF-κB

Isoform

– NF-κB

Pathway

– NF-κB

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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