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Gingerenone A
$30 – $290
Products Details
Product Description
– Gingerenone A is a Nrf2-Gpx4 activator with anti-breast-cancer properties. Gingerenone A results a delayed G2/M in cancer cells, following oxidative stress and senescence responses. Gingerenone A also alleviates ferroptosis in secondary liver injury (SLI) in dextran sodium sulfate (DSS)-induced colitis mice. Gingerenone A can be isolated from Zingiber officinale[1][2].
Web ID
– HY-120912
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H24O5
References
– [1]Yu TJ, et al. Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells. Antioxidants (Basel). 2022 Mar 19;11(3):587.|[2]Chen Y, et al. Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway. J Agric Food Chem. 2022 Oct 5;70(39):12525-12534.
CAS Number
– 128700-97-0
Molecular Weight
– 356.41
Compound Purity
– 98.0
SMILES
– O=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=C(O)C(OC)=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glutathione Peroxidase;Keap1-Nrf2
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
