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Germacrone
Price range: 66 CAD through 336 CAD
Products Details
Product Description
– Germacrone is extracted from Curcuma zedoaria and has anti-inflammatory, anti-androgenic and antiviral activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.
Web ID
– T2945
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H22O
Citations
– 1. Li Z, Wang Z, Dong F, et al. Germacrone Attenuates Hepatic Stellate Cells Activation and Liver Fibrosis via Regulating Multiple Signaling Pathways. Frontiers in Pharmacology. 2021: 2750.
2. Schepetkin, Igor A., et al. Chemical Composition and Immunomodulatory Activity of Essential Oils from Rhododendron albiflorum. Molecules. 26.12 (2021): 3652.
3. Kaduk J A, Gates-Rector S, Blanton T N. Crystal structure of a second polymorph of germacrone, C15H22O. Powder Diffraction. 2022: 1-7.
4. Wang Y, He X, Xue M, et al.Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.Free Radical Research.2023 (just-accepted): 1-36.
5. Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects
References
– Xie XH, et al. Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells. Exp Ther Med. 2014 Nov;8(5):1611-1615.
CAS Number
– 6902-91-6
Molecular Weight
– C15H22O
Compound Purity
– 0.9888
SMILES
– CC(C)=C1CC=C(C)/CCC=C(C)/CC1=O
Pathway
– Microbiology/Virology|||Immunology/Inflammation|||Metabolism
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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