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Gemcitabine-O-Si(di-iso)-O-Mc
$550 – $1,500
Products Details
Product Description
– Gemcitabine-O-Si(di-iso)-O-Mc is a agent-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker[1].
Web ID
– HY-130812
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H36F2N4O7Si
References
– [1]Mathew C. Finniss, et al. A versatile acid-labile linker for antibody–drug conjugate. MedChemComm, Issue 9, 2014.
Molecular Weight
– 558.65
Compound Purity
– 98.79
SMILES
– NC(C=CN1[C@H]2C(F)([C@@H]([C@H](O2)CO[Si](C(C)C)(OCCCCCN3C(C=CC3=O)=O)C(C)C)O)F)=NC1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
