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Products Details
Product Description
– FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity[1].
Web ID
– HY-146595
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H32IN3
References
– [1]Zhong DX, She MT, Guo XC, et al. Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. Eur J Med Chem. 2022;236:114360.
CAS Number
– 2516246-24-3
Molecular Weight
– 513.46
SMILES
– CC1CCN(C2=C3C=CC=CC3=[N+](C)C(/C=C/C4=CC=C(N(C)C)C=C4)=C2)CC1.[I-]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
