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Flumequine-13C3
$548
Only 1000 item(s) left in stock.
Products Details
Product Description
– Flumequine-13C3 is the 13C3 labeled Flumequine. Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
Web ID
– HY-B0526S
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C11 13C3H12FNO3
References
– [1]Giraud E, et al. Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis. J Med Microbiol. 2004 Sep;53(Pt 9):895-901.|[2]Kashida Y, et al. Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice. Toxicol Sci. 2002 Oct;69(2):317-21.|[3]Aller-Morán LM, et al. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015 Dec;103:51-3.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number
– 1185049-09-5
Molecular Weight
– 264.23
SMILES
– O=[13C]1C2=CC(F)=CC3=C2N(C(CC3)C)C=[13C]1[13C](O)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Cancer
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Isotope-Labeled Compounds;Topoisomerase
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
