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Products Details
Product Description
– FAK ligand-Linker Conjugate 1 is a chemical compound designed to facilitate PROTAC-mediated protein degradation. This compound consists of a ligand specifically targeting FAK and a PROTAC linker module, which acts as a recruitment agent for E3 ligases including VHL, CRBN, MDM2, and IAP[1].
Web ID
– T17943
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H28F3N5O6S
References
– Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.
CAS Number
– 2307461-45-4
Molecular Weight
– C25H28F3N5O6S
SMILES
– CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(O)=O)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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