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EZM0414 (TFA)
$500 – $4,600
Products Details
Product Description
– EZM0414 TFA is a potent, selective and orally active inhibitor of SETD2 which is a human histone methyltransferase. EZM0414 TFA has anti-proliferative effects[1].
Web ID
– HY-136328
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H30F4N4O4
References
– [1]John Lampe, et al. Substituted indoles and methods of use thereof. WO2020037079A1.
CAS Number
– 2411759-92-5
Molecular Weight
– 514.51
Compound Purity
– 99.42
SMILES
– O=C(C(N1)=CC2=C1C(C)=CC=C2F)N[C@H]3C[C@@H](N4CCN(C(C)=O)CC4)CCC3.O=C(O)C(F)(F)F
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 200 mg/mL (ultrasonic)|H2O : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histone Methyltransferase
Isoform
– SETD2/KMT3A
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
