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Etomoxir
Price range: 48 CAD through 2,128 CAD
Products Details
Product Description
– Etomoxir is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation by inhibiting CPT-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. Etomoxir has an inhibitory effect on adenine nucleotide translocase and can inhibit macrophage polarization by disrupting CoA homeostasis.
Web ID
– T4535L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H23ClO4
Citations
– 1. Nian Z, Dou Y, Shen Y, et al.Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation.Immunity.2024
References
– Xu FY, et al. Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J Lipid Res. 2003 Feb;44(2):415-23.
CAS Number
– 124083-20-1
Molecular Weight
– C17H23ClO4
Compound Purity
– 0.9939
SMILES
– C(OCC)(=O)[C@@]1(CCCCCCOC2=CC=C(Cl)C=C2)CO1
Pathway
– Oxidation-Reduction|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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