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Product Description
– ERK5-IN-5 (compound 4a) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-5 exhibits good anti-proliferative activity with the IC50 value of 6.23 µg/mL for A549 cells[1].
Web ID
– HY-156450
Shipping
– Room temperature
Molecular Formula
– C19H16ClN3O
References
– [1]Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.
CAS Number
– 2318792-30-0
Molecular Weight
– 337.80
SMILES
– O=C(N1CC=C(C2=CNC3=NC=CC=C32)CC1)C4=CC=C(Cl)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK
Isoform
– ERK5
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
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