Products Details

Product Description

– Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM.

Web ID

– HY-N0637

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H12O6

References

– [1]Zhu GF, et al. Eriodictyol, a plant flavonoid, attenuates LPS-induced acute lung injury through its antioxidative and anti-inflammatory activity. Exp Ther Med. 2015 Dec;10(6):2259-2266. Epub 2015 Oct 23.|[2]Jing X, et al. Eriodictyol Attenuates β-Amyloid 25-35 Peptide-Induced Oxidative Cell Death in Primary Cultured Neurons by Activation of Nrf2. Neurochem Res. 2015 Jul;40(7):1463-71.|[3]Václav Zima, et al. Unraveling the Anti-Influenza Effect of Flavonoids: Experimental Validation of Luteolin and its Congeners as Potent Influenza Endonuclease Inhibitors. Eur J Med Chem. 22 August 2020, 112754.

CAS Number

– 552-58-9

Molecular Weight

– 288.25

Compound Purity

– 99.85

SMILES

– O=C1C[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology

Solubility

– DMSO : 125 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic;warming;heat to 80°C)

Target

– DNA/RNA Synthesis;Endogenous Metabolite;Influenza Virus;Keap1-Nrf2

Isoform

– Human Endogenous Metabolite

Pathway

– Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;NF-κB

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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