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Products Details
Product Description
– Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser[1][2].
Web ID
– HY-N0425
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H30O5
References
– [1]Mariana Alves Reis, et al. Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer. Front Pharmacol. 2020 May 8;11:599.|[2]Wei Jiao, et al. Lathyrane diterpenes from <i>Euphorbia lathyris</i> as modulators of multidrug resistance and their crystal structures. Bioorg Med Chem. 2009 Jul 1;17(13):4786-92.
CAS Number
– 28649-60-7
Molecular Weight
– 350.45
SMILES
– O[C@@H]1[C@]2(CO2)CC[C@@]3([H])[C@](/C=C(C([C@@]4([C@]1([H])[C@H]([C@H](C4)C)O)O)=O)C)([H])C3(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– P-glycoprotein
Pathway
– Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
