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Epothilone D
$90 – $1,000
Products Details
Product Description
– Epothilone D (KOS 862) is a potent microtubule stabilizer.
Web ID
– HY-15278
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H41NO5S
References
– [1]Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.
J Neurosci. 2010 Oct 13;30(41):13861-6.|[2]Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma.
Invest New Drugs. 2012 Dec;30(6):2294-302.
CAS Number
– 189453-10-9
Molecular Weight
– 491.68
Compound Purity
– 99.93
SMILES
– O=C(O[C@@H](C/C=C(CCC[C@@H]([C@@H]([C@H](C1=O)C)O)C)/C)/C(C)=C/C2=CSC(C)=N2)C[C@@H](C1(C)C)O
Clinical Information
– Phase 2
Research Area
– Cancer; Infection
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Antibiotic;Bacterial;Fungal;Microtubule/Tubulin
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
