(-)-Epigallocatechin Gallate
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(-)-Epigallocatechin Gallate

SKU T2988-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 221 CAD

Products Details

Product Description

– (-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.

Web ID

– T2988

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H18O11

Citations

– 1. Zhou H, Ning Y, Zeng G, et al. Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT. Oncology Reports. 2021, 45(4): 1-1. 2. Lu J, Lu Z, Liu L, et al. Identification of crocin as a new hIAPP amyloid inhibitor via a simple yet highly biospecific screening system. Chemistry & Biodiversity. 2021 3. Cheng M, Yan X, Wu Y, et al.Qingke Pingchuan granules alleviate airway inflammation in COPD exacerbation by inhibiting neutrophil extracellular traps in mice.Phytomedicine.2024: 156283. 4. Zhang Z, Zheng C, Gu X, et al.Cardiotoxicity of tris (2-chloroethyl) phosphate exposure: Insights into the role of oxygen sensor mediated energy metabolism remodeling.Journal of Hazardous Materials.2025: 137113. 5. Li X, Bi L, Zhang S, et al.Single‐Molecule Insight Into α‐Synuclein Fibril Structure and Mechanics Modulated by Chemical Compounds.Advanced Science.2416721

References

– Wu D, et al. Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway. Cancer Cell Int. 2019 Feb 28;19:43.

CAS Number

– 989-51-5

Molecular Weight

– C22H18O11

Compound Purity

– 0.9926

SMILES

– O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C(O)=C4

Pathway

– Autophagy|||NF-κB|||Immunology/Inflammation|||Apoptosis|||Microbiology/Virology|||Metabolism|||Proteases/Proteasome

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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