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EOC317
Price range: 190 CAD through 702 CAD
Products Details
Product Description
– EOC317 (ACTB-1003) is an oral kinase inhibitor with IC50 values of 6 nM, 2 nM, and 4 nM for FGFR1, VEGFR2, and Tie-2, respectively.
Web ID
– T4318
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H26F5N7O3
References
– Patel K, et al. ACTB-1003: An oral kinase inhibitor targeting cancer mutations (FGFR), angiogenesis (VEGFR2, TEK), and induction of apoptosis (RSK and p70S6K). Journal of Clinicalal Oncology 28, no. 15 DOI: 10.1200/jco.2010.28.15_suppl.e13665
CAS Number
– 939805-30-8
Molecular Weight
– C27H26F5N7O3
Compound Purity
– 0.98
SMILES
– COCc1c(CN2CCOCC2)n2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)c(F)c1
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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