Ensartinib hydrochloride
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Ensartinib hydrochloride

SKU T22324-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 96 CAD through 1,579 CAD

Products Details

Product Description

– Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.

Web ID

– T22324

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H29Cl4FN6O3

References

– Li T, et al. Chin Clin Oncol. 2019, 8(S1):S

CAS Number

– 2137030-98-7

Molecular Weight

– C26H29Cl4FN6O3

Compound Purity

– 0.9929

SMILES

– Cl.Cl.C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl

Target

– c-Myc

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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