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Engeletin
Price range: 66 CAD through 677 CAD
Products Details
Product Description
– 1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
Web ID
– T6S0840
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H22O10
Citations
– 1. Feng M, Liu L, Wang J, et al.The Molecular Mechanisms Study of Engeletin Suppresses RANKL-Induced Osteoclastogenesis and Inhibits Ovariectomized Murine Model Bone Loss.Journal of Inflammation Research.2023: 2255-2270.
2. Chen W, Zhang L, Zhong G, et al.Regulation of microglia inflammation and oligodendrocyte demyelination by Engeletin via the TLR4/RRP9/NF-κB pathway after spinal cord injury.Pharmacological Research.2024: 107448.
References
– Huang H , Cheng Z , Shi H , et al. Isolation and Characterization of Two Flavonoids, Engeletin and Astilbin, from the Leaves of Engelhardia roxburghiana and Their Potential Anti-inflammatory Properties[J]. Journal of Agricultural and Food Chemistry, 2011, 59(9):4562-4569.
CAS Number
– 572-31-6
Molecular Weight
– C21H22O10
Compound Purity
– 0.9972
SMILES
– C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O
Pathway
– Metabolism|||NF-κB|||Endocrinology/Hormones
Product type
– Natural Product
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