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EML 425
$110 – $980
Products Details
Product Description
– EML425 is a potent and selective CREB binding protein (CBP)/p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively.
Web ID
– HY-110263
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H24N2O4
References
– [1]Milite C, et al. A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach. J Med Chem. 2015 Mar 26;58(6):2779-98.
CAS Number
– 1675821-32-5
Molecular Weight
– 440.49
Compound Purity
– 98.16
SMILES
– O=C(N(C(N(CC1=CC=CC=C1)C/2=O)=O)CC3=CC=CC=C3)C2=C/C4=C(C=C(O)C=C4C)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Neurological Disease; Cardiovascular Disease
Solubility
– DMSO : ≥ 250 mg/mL
Target
– Epigenetic Reader Domain;Histone Acetyltransferase
Isoform
– CBP/p300;TIP60
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
