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Eltanexor
Price range: 96 CAD through 3,072 CAD
Products Details
Product Description
– Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines.
Web ID
– T11766L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H10F6N6O
References
– Vercruysse T et al. The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. Clin Cancer Res. 2016 Oct 25.
CAS Number
– 1642300-52-4
Molecular Weight
– C17H10F6N6O
Compound Purity
– 0.9976
SMILES
– NC(=O)C(=Cn1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cncnc1
Target
– Src
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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