Download Files:
Eliglustat
$66 – $581
Products Details
Product Description
– Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
Web ID
– HY-14885
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C23H36N2O4
Citations
– Cell Death Dis. 2021 Oct 6;12(10):911.|EMBO J. 2022 Dec 12;e110553.|Nat Commun. 2020 Aug 27;11(1):4279.|bioRxiv. 2021 Feb 2.|Cancer Discov. 2022 Nov 4;CD-22-0535.|Immunity. 2021 Jan 12;54(1):132-150.e9.|PLoS One. 2021 Oct 25;16(10):e0247211.|Stem Cells Transl Med. 2021 Mar 3.
References
– [1]McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-68.
CAS Number
– 491833-29-5
Molecular Weight
– 404.54
Compound Purity
– 99.95
SMILES
– CCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O
Clinical Information
– Launched
Research Area
– Metabolic Disease; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
