EGFR/ErbB-2/ErbB-4 inhibitor-2

SKU T21954-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 110 CAD through 1,808 CAD

Products Details

Product Description

– EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable compound that inhibits EGFR and c-ErbB2 with IC50 values of 20 nM and 79 nM, respectively.

Web ID

– T21954

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H21N3O3

References

– Cockerill S , Stubberfield C , Stables J , et al. Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2.[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 32( 11):no-no.

CAS Number

– 179248-61-4

Molecular Weight

– C23H21N3O3

Compound Purity

– 0.9955

SMILES

– COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC

Pathway

– Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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