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Products Details
Product Description
– EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
Web ID
– T27242
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H15F2NO
References
– Lelli D, Pedone C, Sahebkar A. Curcumin and treatment of melanoma: The potential role of microRNAs. Biomed Pharmacother. 2017 Apr;88:832-834.
CAS Number
– 342808-40-6
Molecular Weight
– C19H15F2NO
Compound Purity
– 0.9847
SMILES
– Fc1ccccc1C=C1/CNCC(=C/c2ccccc2F)C1=O
Pathway
– Apoptosis|||MAPK|||Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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