Products Details

Product Description

– eeAChE-IN-2 is a potent eeAChE inhibitor with an IC50 value of 2 nM.

Web ID

– HY-132904

Shipping

– Room temperature

Molecular Formula

– C37H40N8O5S

References

– [1]Javed MA, et al. Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer’s Disease. ACS Chem Neurosci. 2021 Nov 3;12(21):4123-4143.

CAS Number

– 2763366-33-0

Molecular Weight

– 708.83

SMILES

– COC1=CC=C(C=C1)C2=NC(NC3=CC=C(C=C3)S(N)(=O)=O)=NC(C)=C2CC(NCCNCC(NC4=C5C=CC=CC5=NC6=C4CCCC6)=O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Isoform

– AChE

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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