eCF506

SKU HY-112096-1 mg Category Tags , ,

$52$715

Products Details

Product Description

– eCF506 is a highly potent and orally bioavailable inhibitor of the non-receptor tyrosine kinase Src with an IC50 of less than 0.5 nM.

Web ID

– HY-112096

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C26H38N8O3

References

– [1]Fraser C, et al. Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase. J Med Chem. 2016 May 26;59(10):4697-710.

CAS Number

– 1914078-41-3

Molecular Weight

– 510.63

Compound Purity

– 99.30

SMILES

– NC1=C2C(C3=CC(OC)=C(NC(OC(C)(C)C)=O)C=C3)=NN(CCN4CCC(N(C)C)CC4)C2=NC=N1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 62.5 mg/mL (ultrasonic)|H2O : 0.1 mg/mL (ultrasonic)

Target

– Src

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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