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Product Description
– EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1[1].
Web ID
– HY-128940
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H46N14O14S
References
– [1]Christopher Paul Leamon, et al. Binding ligand linked drug delivery conjugates of tubulysins. WO2011069116A1.
CAS Number
– 625827-91-0
Molecular Weight
– 930.90
SMILES
– O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)C=C3)=CNC2=NC(N)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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