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EB-42486
$380 – $2,850
Products Details
Product Description
– EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).
Web ID
– HY-142647
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H22N8O
References
– [1]Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839.
CAS Number
– 2390475-81-5
Molecular Weight
– 414.46
Compound Purity
– 99.62
SMILES
– O=C(C1=C(C)N(C)C2=NN=NN2C1(C)C)NC3=CC4=C(NN=C4C5=CC=CC=C5)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– LRRK2
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
