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Products Details
Product Description
– E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Web ID
– HY-128806
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H32N2O6
References
– [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CAS Number
– 87304-15-2
Molecular Weight
– 408.49
SMILES
– CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](NC(OC(C)(C)C)=O)CC1=CC=CC=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Isoform
– IAP
Pathway
– PROTAC
Product type
– Reference compound
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