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Products Details
Product Description
– E3 ligase Ligand 22 (compound 139) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1].
Web ID
– HY-144983
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H34N6O4
References
– [1]Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1.
CAS Number
– 2377849-57-3
Molecular Weight
– 518.61
SMILES
– CC1(CCC1)CN2CCC(CC2)N3C=C(C=N3)CNC4=C5C(N(C(C5=CC=C4)=O)C6CCC(NC6=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
