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Products Details
Product Description
– E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Web ID
– HY-128811
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H52N4O7
References
– [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CAS Number
– 2241489-43-8
Molecular Weight
– 676.84
SMILES
– O=C(N[C@@H]1CCCC2=C1C=CC=C2)[C@H]3N(C[C@H](C3)OC4=CC=CC(O)=C4)C([C@@H](NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)C5CCCCC5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
