(E)-Cardamonin
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(E)-Cardamonin

SKU T2994-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 453 CAD

Products Details

Product Description

– (E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM. It has received growing attention from the scientific community due to the expectations toward its benefits to human health.

Web ID

– T2994

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H14O4

Citations

– 1. He J, Zhou H, Meng J, et al. Cardamonin retards progression of autosomal dominant polycystic kidney disease via inhibiting renal cyst growth and interstitial fibrosis. Pharmacological Research. 2020: 104751

References

– Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21(9). pii: E1145.

CAS Number

– 19309-14-9

Molecular Weight

– C16H14O4

Compound Purity

– 0.9808

SMILES

– C(/C=C/C1=CC=CC=C1)(=O)C2=C(OC)C=C(O)C=C2O

Pathway

– Apoptosis|||Membrane transporter/Ion channel

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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